BIOTIA‑DX ISOLATE and OUTBREAK

Affordable microbial sequencing to support clinical decision-making. Identify species, predict resistance, and detect outbreaks.

Key Features

BIOTIA-DX Isolate & Outbreak provides rapid genomic analysis of bacterial and fungal isolates to support infection control and antimicrobial stewardship. Get species and strain identification, antimicrobial resistance profiling, and outbreak cluster detection with unmatched accuracy and cost-efficiency. Detect, track, and respond to infectious threats with confidence.

BIOTIA-DX OUTBREAK

Track HAIs Before They Spread

BIOTIA-DX OUTBREAK provides critical information to infection control teams. Find clusters of closely related pathogens and identify sources of transmission. Track changing drug resistance patterns over time. Compare your facilities samples to publicly available outbreak genomes to identify community acquired vs facility acquired outbreaks.

Key Features

  • Identify clonal complexes of microbial isolates
  • Phylogenetic trees to visualize organism relatedness
  • Custom cgMLSTs determine relatedness based on thousands of genomic markers
  • Grow analysis as more samples are collected
  • Find and track transmission patterns
  • Compare to community acquired microbes

This software is for research use only

BIOTIA-DX ISOLATE

Analyze Microbial Isolates

BIOTIA-DX Isolate brings best in class genomic analysis to pathogen isolate sequencing. Remove any ambiguity about your isolated cultures with deep taxonomic characterization and genomic resistance analysis. Identify precise strain types for different species and, with BIOTIA-DX Outbreak, find outbreak clusters.

Includes the BIOTIA-DX RESISTANCE module for genetic prediction of antimicrobial resistance.

Key Features

  • Determine species and strain from a database of thousands of organisms
  • Predict antimicrobial resistance with BIOTIA-DX RESISTANCE
  • Tag samples with LPSN taxonomy
  • Assemble and annotate genome for downstream analysis
  • Determine strain through custom cgMLST
  • Characterize plasmids such as those that carry mecA
  • Disambiguate tricky species groups like Ecoli Shigella and Klebsiella
  • Works with BIOTIA-DX Outbreak for outbreak cluster analysis
  • Validated on Illumina and ONT data

Specialized tools available for certain pathogens, including: Tuberculosis, Acinetobacter

For research use only

Clinical Impact

  • Rapidly detect and contain outbreak hospital-acquired infections before they spread
  • Use genomic resistance profiling to inform treatment for multi-drug resistant infections
  • Accurate strain identification to support treatment of rare or hard to culture bacteria and fungi
  • Power pathogen surveillance studies, AMR discovery, and translational applications

Logistics

  • Send isolates as cell pellets, cryo-stock, or on slant
  • Receive reports in 5-10 days
  • Bioinformatic outputs available
  • software-only solution available
  • Outbreak analysis is included at no additional cost
  • Outbreak aanlysis can be updated with new samples
  • Works with clinical isolates and screening cultures

Predict antimicrobial resistance with best-in-class accuracy

BIOTIA-DX RESISTANCE achieved the best antimicrobial resistance accuracy at CAMDA 2025. Read our preprint on bioRxiv.

Simple Pricing

  • $200 per bacterial isolate (sequencing + analysis)
  • $240 per fungal isolate (sequencing + analysis)
  • Works with in-house sequencing: $40 for analysis only

  • No minimum number of samples
  • Outbreak analysis at no additional cost

Developed with MAYO Clinic

Co-developed with the Mayo Clinic to strengthen the clinical components of BIOTIA-DX and validate our approach on clinical data.

There is great promise in using sequencing for infectious disease diagnostics, especially for challenging or drug resistant infections.

Interested? Get in touch.